SLU-PP-332

Description

⚠️ LABORATORY RESEARCH USE ONLY — NOT FOR HUMAN OR ANIMAL CONSUMPTION
This product is supplied exclusively for in vitro and laboratory research by qualified personnel. It is not approved by the FDA for any clinical, therapeutic, diagnostic, cosmetic, dietary, or veterinary application.

SLU-PP-332 (Capsule Reagent)

SLU-PP-332 is a synthetic benzohydrazide small molecule, (E)-4-hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide, characterized in published literature as a pan-agonist of the estrogen-related receptors, with reported EC50 values of 98 nM (ERRα), 230 nM (ERRβ), and 430 nM (ERRγ). The ERRs are orphan nuclear receptors studied for their role in transcriptional regulation of cellular energy-metabolism gene programs. SLU-PP-332 is supplied in pre-measured capsule form for laboratories that require repeatable microgram-scale reagent quantities for nuclear-receptor, mitochondrial, and analytical workflows.

Product Specifications

Product Name	SLU-PP-332
Synonyms	ERR pan-agonist 332; SR9861
CAS Number	303760-60-3
PubChem CID	5338394
Molecular Formula	C₁₈H₁₄N₂O₂
Molecular Weight	290.32 g/mol
Quantity	500 mcg per capsule; see label for capsule count
Form	Pre-measured capsule (inert containment vehicle)
Purity	≥98% by HPLC; see third-party COA
Classification	Synthetic small molecule — research reagent

Research Applications

SLU-PP-332 is used in in vitro and preclinical model systems to investigate:

• ERRα/β/γ nuclear-receptor binding and transcriptional-activation assays
• ERR target-gene expression readouts (e.g., PDK4) in cell-culture models
• Mitochondrial respiration and cellular bioenergetics assays in skeletal-muscle cell lines
• Nuclear-receptor selectivity profiling and analytical method development

Format & Handling

This reagent is supplied in pre-measured capsule form. The capsule shell serves as an inert containment and metering vehicle for the research material, allowing precise, repeatable quantities to be transferred to laboratory workflows (for example, dissolution or extraction into an appropriate solvent or buffer prior to analysis). The capsule format is a packaging convenience and does not indicate suitability for ingestion or any in vivo use. Store sealed containers in a cool, dry location protected from light; follow standard laboratory handling procedures for chemical reagents.

Published Literature

1. Billon C, Sitaula S, Banerjee S, et al. Synthetic ERRα/β/γ agonist induces an ERRα-dependent acute aerobic exercise response and enhances exercise capacity. ACS Chem Biol. 2023;18(4):756–771.
2. Billon C, Schoepke E, Avdagic A, et al. A synthetic ERR agonist alleviates metabolic syndrome. J Pharmacol Exp Ther. 2024;388(2):232–240.

The references above are provided for bibliographic purposes only and describe work conducted by independent investigators. They do not characterize this product and do not constitute any representation about its properties or use.

Research Use Only Statement

SLU-PP-332 (Capsule Reagent) is a chemical reagent supplied solely for laboratory research and analytical purposes. It is not a drug, dietary supplement, cosmetic, food additive, or medical device, and it has not been evaluated by the U.S. Food and Drug Administration. It is not intended to diagnose, treat, cure, or prevent any disease in humans or animals. Peptide Minds is a research chemical supplier and is not a pharmacy, compounding facility, or medical provider. The purchaser is responsible for ensuring the material is handled by trained personnel in accordance with all applicable laws, regulations, and institutional requirements, including safe storage, use, and disposal.

Frequently Asked Questions

What is SLU-PP-332?

SLU-PP-332 (CAS 303760-60-3) is a synthetic small molecule characterized in published literature as a pan estrogen-related receptor (ERRα/β/γ) agonist. Peptide Minds supplies it as a pre-measured capsule reagent for laboratory research use only.

What is the molecular formula and weight?

The molecular formula is C18H14N2O2 and the molecular weight is 290.32 g/mol.

Why is this reagent supplied in capsule form?

The capsule shell is an inert containment and metering vehicle that provides repeatable pre-measured quantities for laboratory workflows. The format is a packaging convenience only and does not indicate suitability for ingestion or any in vivo use.

Is a COA provided?

Yes. Each lot is third-party tested and supplied with a Certificate of Analysis documenting identity and purity (≥98% by HPLC).

Is SLU-PP-332 approved for human use?

No. SLU-PP-332 is supplied strictly as a research chemical for laboratory use by qualified researchers. It is not a drug, dietary supplement, or consumer product, is not approved by the FDA for any use, and is not intended for human or veterinary consumption.