Pregnenolone
$50.00
Choose reagent-grade Pregnenolone Micronised — 25 mg per capsule, 60 capsules per container.
- 🔬 Micronised Pregnenolone — endogenous neurosteroid & master steroid precursor
- 💊 25 mg per capsule | 60 capsules per container
- ✅ Purity: ≥99% HPLC-verified | Test Method: HPLC
- ⚖️ Molecular Formula: C₂₁H₃₂O₂ | CAS: 145-13-1
- 🧪 Suitable for steroidogenesis, neurosteroid, cognitive & adrenal biology research
- 📋 Full Certificate of Analysis (CoA) included per batch | Batch No. PM-PREG-3601
- 🏭 GMP-compliant manufacturing | Third-party tested
- ⚠️ For in vitro laboratory research use only — Not for human or animal consumption
Description
⚠️ LABORATORY RESEARCH USE ONLY
NOT FOR HUMAN OR ANIMAL CONSUMPTION
This product is intended exclusively for in vitro research and analytical applications in professional laboratory settings.
NOT approved by FDA for human use. NOT for clinical, diagnostic, or therapeutic purposes.
Pregnenolone (Micronised — Reference Grade)
Reagent-Grade Research Compound | SKU: PM-PREG-3601
| NOTICE: This product is sold exclusively as a reagent-grade research compound for in-vitro laboratory, analytical, and scientific investigation purposes. It is not approved by the FDA for any clinical, therapeutic, diagnostic, or veterinary application. Not for human consumption. |
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Product Specifications
| Parameter | Value |
|---|---|
| Compound Name | Pregnenolone Micronised |
| Category | Endogenous neurosteroid; steroidogenesis precursor (research designation) |
| Strength Per Capsule | 25 mg |
| Unit Count Per Container | 60 capsules |
| Batch No. | PM-PREG-3601 |
| Lot No. | — |
| CAS Number | 145-13-1 |
| Molecular Formula | C₂₁H₃₂O₂ |
| Molecular Weight | — |
| Form | Micronised encapsulated powder |
| Purity | ≥99% (HPLC-verified, expected) |
| Test Method | HPLC |
| Available Sizes | 60 capsules (25 mg each) |
Storage & Handling
| Condition | Recommendation |
|---|---|
| Temperature | Store in a cool, dry place away from direct sunlight |
| Container | Keep container tightly closed at all times |
| Access | Keep out of reach of children |
| Integrity | Do not use if safety seal is damaged or missing |
| Personnel | For use by qualified research professionals only |
Structural Notes
| Feature | Description |
|---|---|
| Micronised form | Reduced particle size for improved dispersion in aqueous research buffers and in vitro assay systems |
| Steroid backbone | C21 pregnane skeleton; biosynthetic precursor to all major steroid hormone classes |
| Ketone & hydroxyl groups | 3β-hydroxy-5-pregnen-20-one configuration; key structural feature for receptor binding studies |
| Reference-grade purity (≥99%) | Minimizes background interference in sensitive biochemical and steroidogenesis assays |
⚠️Research Context
Pregnenolone Micronised is a reference-grade neurosteroid compound of research interest in the following areas as described in published scientific literature:
| Research Area | Pathway / System of Interest |
|---|---|
| Steroidogenesis pathway research | Biosynthetic precursor to progesterone, DHEA, cortisol & testosterone |
| Neurosteroid research models | GABA-A / NMDA receptor modulation studies |
| Cognitive & memory research models | Hippocampal neuroplasticity pathway investigations |
| Adrenal biology studies | HPA axis steroid biosynthesis models |
| Aging & longevity research | Age-related steroidogenic decline studies |
| Metabolic pathway analysis | Cholesterol-to-steroid conversion cascade models |
The above are reported areas of scientific investigation from peer-reviewed literature and are provided for researcher reference only.
Quality Documentation
Each batch is accompanied by a Certificate of Analysis (CoA) including:
- HPLC purity analysis (≥99%)
- Identity confirmation (molecular weight verification)
- Endotoxin testing (LAL method)
- Independent third-party batch verification
Current batch documentation:
| Size | Batch No. | Lot No. | Test Method | Verification |
|---|---|---|---|---|
| 60 caps × 25 mg | PM-PREG-3601 | On file | HPLC | CoA on file |
Published Literature
The following peer-reviewed publications describe investigations involving this compound. Citations are provided for researcher reference only and do not constitute endorsement of any application.
- Vallée M, Mayo W, Le Moal M. Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging. Brain Res Rev. 2001;37(1-3):301–312. doi:10.1016/S0165-0173(01)00135-7
- Baulieu EE. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology. 1998;23(8):963–987. doi:10.1016/S0306-4530(98)00071-7
- Majewska MD. Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance. Prog Neurobiol. 1992;38(4):379–395. doi:10.1016/0301-0082(92)90025-a
- Marx CE, Stevens RD, Shampine LJ, et al. Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics. Neuropsychopharmacology. 2006;31(6):1249–1263. doi:10.1038/sj.npp.1300952
- Cascio C, Russo D, Drago G, et al. Biosynthesis of neurosteroids in the central and peripheral nervous system: physiological and pathological implications. Curr Drug Targets CNS Neurol Disord. 2002;1(4):361–374. doi:10.2174/1568007023339195
Regulatory & Compliance Statement
| This product is intended exclusively for in-vitro research, laboratory testing, and analytical applications. It is not intended for use in humans, animals, food products, cosmetics, or any clinical/diagnostic application. Products have not been evaluated by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. By purchasing this product, the buyer represents that they are at least 21 years of age and that the product will be used solely for lawful research purposes by qualified personnel in compliance with all applicable regulations. |
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Disclaimer
“Purchase of this product signifies an agreement that it will be used solely for legitimate laboratory research purposes by qualified individuals trained in laboratory procedures and safety. The buyer assumes all responsibility for the proper handling, storage, use, and disposal of this product. The seller makes no claims regarding the suitability of this product for any particular research application beyond its specified chemical identity and purity. This product has not been evaluated by the Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease or condition. All product descriptions and details found on this website are intended for educational, research and informational purposes only.”
Additional information
| Quantity | 1 VIAL, 2 VIALS, 5 VIALS, 10 VIALS |
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| Size | 10 MG |












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