Kisspeptin-10 (KP-10) 10mg Peptide

Description

Research-Grade Kisspeptin-10 for Neuroendocrine and Reproductive Research

Kisspeptin-10 (KP-10) is a synthetic decapeptide widely used in neuroendocrine and reproductive biology research. Derived from the C-terminal region of the endogenous KISS1 protein, it represents the shortest peptide fragment capable of fully activating the KISS1 receptor (KISS1R/GPR54). Because of its well-characterized receptor activity, Kisspeptin-10 has become a valuable research tool for studying hypothalamic signaling, reproductive hormone regulation, and cellular communication within the hypothalamic-pituitary-gonadal (HPG) axis.

This product contains 10mg of research-grade Kisspeptin-10 supplied as a white to off-white lyophilized powder with ≥98% HPLC-verified purity. Independently tested by Janoshik Analytical, every batch is verified for purity and identity, providing researchers with confidence in the consistency and quality of their laboratory materials. If you’re looking to buy Kisspeptin peptide for scientific research, this peptide is manufactured exclusively for laboratory and preclinical investigations.

What is Kisspeptin-10?

Kisspeptin-10 is a synthetic version of amino acids 45-54 of metastin, the naturally occurring peptide encoded by the KISS1 gene. Although it consists of only ten amino acids, this fragment retains full receptor-binding activity and is commonly used as a reference agonist in studies involving KISS1R signaling.

Since the discovery of the kisspeptin signaling system, researchers have investigated its role in reproductive neuroendocrinology, hormone regulation, and neuronal communication. Today, Kisspeptin-10 remains an important research peptide for exploring the molecular mechanisms that regulate GnRH neuron activity and endocrine signaling in controlled laboratory settings.

Key Research Applications

Kisspeptin-10 has been extensively studied across multiple areas of laboratory research, particularly those involving neuroendocrine signaling and receptor biology.

Current research applications include:

• KISS1R (GPR54) receptor activation studies
• GnRH neuronal signaling and HPG axis research
• Calcium mobilization and MAPK pathway analysis
• Comparative studies with Kp-54, Kp-14, and Kp-13
• Tumor biology and metastasis-related research
• Reference standard for peptide characterization and analytical methods

Researchers searching for Kisspeptin peptide for research or Kisspeptin hormone peptide frequently use KP-10 as a well-established model compound because of its defined structure and reliable receptor activity.

Product Specifications

Quality and Laboratory Handling

Every batch undergoes independent analytical testing to verify both purity and identity before release. Quality control includes reverse-phase HPLC for purity analysis and mass spectrometry for molecular confirmation. Batch-specific Certificates of Analysis (COAs) are available to support laboratory documentation and quality assurance requirements.

For long-term stability, store the lyophilized peptide at -20°C in a sealed container, protected from moisture and direct light. After reconstitution, laboratory protocols generally recommend refrigerated storage at 2-8°C for short-term use while avoiding repeated freeze-thaw cycles to help preserve peptide integrity.

Research Background

Kisspeptin was first identified through studies of the KISS1 gene, originally recognized for its role in metastasis suppression. Later discoveries established the KISS1/KISS1R signaling system as a central area of reproductive neuroendocrine research, particularly for investigating GnRH neuron regulation and hormone signaling pathways.

Researchers also compare Kisspeptin vs GnRH to better understand how kisspeptin functions upstream of GnRH neurons within the HPG axis. While searches for terms such as Kisspeptin fertility, Kisspeptin peptide benefits, or Kisspeptin peptide dosage are common, these topics remain investigational, and no approved therapeutic applications have been established.

Research Use Only

This product is supplied exclusively for qualified laboratory researchers and institutional research facilities.

It is not intended for:

• Human consumption
• Veterinary use
• Clinical applications
• Dietary supplements
• Cosmetic products
• Therapeutic or diagnostic purposes

Individuals searching for Kisspeptin peptide supplement or consumer applications should note that this product is available solely for laboratory research.

Compliance Statement

Kisspeptin-10 is an investigational research compound intended exclusively for in vitro laboratory and preclinical research. It is not approved by the U.S. Food and Drug Administration (FDA) or any other regulatory authority for human or veterinary use and is not intended to diagnose, treat, cure, or prevent any disease. Purchase is limited to qualified researchers and institutions conducting lawful scientific investigations.

Frequently Asked Questions

1. What is Kisspeptin-10 used for in research?

Kisspeptin-10 is primarily used to study KISS1R receptor signaling, GnRH neuron activity, reproductive neuroendocrinology, and hormone regulation in laboratory settings.

2. What is the purity of this Kisspeptin-10 peptide?

Each vial contains 10mg of Kisspeptin-10 with ≥98% purity, verified by reverse-phase HPLC and independently tested by Janoshik Analytical.

3. How should Kisspeptin-10 be stored?

Store the lyophilized peptide at -20°C, protected from light and moisture. Reconstituted solutions should be refrigerated at 2-8°C for short-term laboratory use.

4. Is Kisspeptin-10 approved for human use?

No. Kisspeptin-10 is an investigational research-use-only peptide and is not approved for human or veterinary administration.

5. What is the difference between Kisspeptin and GnRH?

Kisspeptin acts upstream of GnRH neurons, helping researchers investigate the signaling pathways that regulate GnRH release and the broader hypothalamic-pituitary-gonadal axis in preclinical studies.