CJC-1295 no DAC
$58.00
Description
What is CJC-1295 (No DAC)?
CJC-1295 (No DAC) is a synthetic peptide analog of Growth Hormone Releasing Hormone (GHRH) designed to stimulate the pituitary gland to release growth hormone (GH). Unlike CJC-1295 with DAC (Drug Affinity Complex), the “No DAC” version lacks the stabilizing modification, resulting in a shorter half-life but providing a pulsatile release of GH that mimics natural physiological secretion.
This property makes it particularly useful in research studies examining natural GH pulsatility, metabolic functions, and regenerative processes.
Summary Table
| Attribute | Details |
|---|---|
| Product Name | CJC-1295 (No DAC) |
| Classification | Synthetic Growth Hormone Releasing Hormone (GHRH) analog |
| Molecular Formula | C152H252N44O42 |
| Molecular Weight | ~3357.9 g/mol |
| CAS Number | 863288-34-0 |
| Sequence | Modified GHRH (1-29) fragment |
| Half-life | ~30 minutes (without DAC) |
| Storage | -20°C (lyophilized), reconstitute in bacteriostatic water |
Mechanism of Action
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CJC-1295 (No DAC) binds to the GHRH receptor on pituitary somatotrophs.
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This binding triggers adenylate cyclase activation, increasing cAMP levels.
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Elevated cAMP stimulates growth hormone synthesis and release.
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Unlike the DAC-modified version (long-acting), CJC-1295 (No DAC) promotes short-term GH pulses similar to endogenous secretion patterns.
Key Point: This distinction makes it highly relevant for research models focusing on short-term GH effects, circadian regulation, and tissue repair mechanisms.
Research Applications
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Growth Hormone Secretion Studies
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Analysis of pulsatile vs. sustained GH release.
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Comparative studies with DAC-modified peptides.
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Metabolic Research
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Insulin sensitivity and glucose metabolism.
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Lipolysis and fat oxidation pathways.
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Musculoskeletal Studies
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Effects on muscle repair and recovery.
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Bone density and connective tissue regeneration.
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Neuroprotective & Cognitive Function Research
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Investigating GH/IGF-1 axis in memory and neuroplasticity.
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Anti-Aging & Cellular Repair Studies
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Role in mitochondrial health.
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Collagen synthesis and skin physiology research.
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Safety & Tolerability
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Common Research Observations:
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Mild flushing
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Temporary injection site reactions
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Short-lived fatigue
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Comparison with CJC-1295 DAC:
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No DAC = shorter half-life, reduced systemic accumulation.
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Considered safer in studies requiring controlled, acute GH release.
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⚠️ Disclaimer: This compound is intended strictly for research purposes. It is not approved for human consumption or therapeutic use.
Explore our complete catalog of high-purity, third-party tested research compounds by visiting our main shop page for all your laboratory needs.
Additional information
| Size | 5 MG |
|---|---|
| Quantity | 1 VIAL, 2 VIALS, 5 VIALS, 10 VIALS |
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