CJC-1295 no DAC
$58.00
Description
⚠️ LABORATORY RESEARCH USE ONLY
NOT FOR HUMAN OR ANIMAL CONSUMPTION
This product is intended exclusively for in vitro research and analytical applications in professional laboratory settings.
NOT approved by FDA for human use. NOT for clinical, diagnostic, or therapeutic purposes.
What is CJC-1295 (No DAC)?
CJC-1295 (No DAC) is a synthetic peptide analog of Growth Hormone Releasing Hormone (GHRH) designed to stimulate the pituitary gland to release growth hormone (GH). Unlike CJC-1295 with DAC (Drug Affinity Complex), the “No DAC” version lacks the stabilizing modification, resulting in a shorter half-life but providing a pulsatile release of GH that mimics natural physiological secretion.
This property makes it particularly useful in research studies examining natural GH pulsatility, metabolic functions, and regenerative processes.
Summary Table
| Attribute | Details |
|---|---|
| Product Name | CJC-1295 (No DAC) |
| Classification | Synthetic Growth Hormone Releasing Hormone (GHRH) analog |
| Molecular Formula | C152H252N44O42 |
| Molecular Weight | ~3357.9 g/mol |
| CAS Number | 863288-34-0 |
| Sequence | Modified GHRH (1-29) fragment |
| Half-life | ~30 minutes (without DAC) |
| Storage | -20°C (lyophilized), reconstitute in bacteriostatic water |
Mechanism of Action
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CJC-1295 (No DAC) binds to the GHRH receptor on pituitary somatotrophs.
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This binding triggers adenylate cyclase activation, increasing cAMP levels.
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Elevated cAMP stimulates growth hormone synthesis and release.
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Unlike the DAC-modified version (long-acting), CJC-1295 (No DAC) promotes short-term GH pulses similar to endogenous secretion patterns.
Key Point: This distinction makes it highly relevant for research models focusing on short-term GH effects, circadian regulation, and tissue repair mechanisms.
Research Applications
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Growth Hormone Secretion Studies
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Analysis of pulsatile vs. sustained GH release.
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Comparative studies with DAC-modified peptides.
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Metabolic Research
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Insulin sensitivity and glucose metabolism.
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Lipolysis and fat oxidation pathways.
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Musculoskeletal Studies
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Effects on muscle repair and recovery.
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Bone density and connective tissue regeneration.
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Neuroprotective & Cognitive Function Research
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Investigating GH/IGF-1 axis in memory and neuroplasticity.
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Anti-Aging & Cellular Repair Studies
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Role in mitochondrial health.
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Collagen synthesis and skin physiology research.
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Safety & Tolerability
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Common Research Observations:
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Mild flushing
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Temporary injection site reactions
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Short-lived fatigue
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Comparison with CJC-1295 DAC:
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No DAC = shorter half-life, reduced systemic accumulation.
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Considered safer in studies requiring controlled, acute GH release.
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⚠️ Disclaimer: This compound is intended strictly for research purposes. It is not approved for human consumption or therapeutic use.
Explore our complete catalog of high-purity, third-party tested research compounds by visiting our main shop page for all your laboratory needs.
Additional information
| Size | 5 MG |
|---|---|
| Quantity | 1 VIAL, 2 VIALS, 5 VIALS, 10 VIALS |
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